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Here are a two facts and an assumption: Fact 1: Senescent cells accumulate with age...evidence is overwhelming that the percentage of senescent cells (by beta-galactosidase staining) increases in tissues of older creatures
Fact 2: Inflammation associated with the increased number of senescent cells as we age is causing tissue damage, loss of tissue function, and ultimately "aging"
Assumption: Senescent cells express and secrete cytokines that promote the recruitment of immune cells, which then cause inflammation, part of the mechanism by which the senescent cell is removed so that other newer, younger, healthier cells can replace it.
QUESTION: If inflammation is supposed to be removing senescent cells, and inflammation is causing tissue damage that leads to aging, why are we seeing more senescent cells in older tissue? I would have expected that a robust inflammatory response would have eliminated the accumulated senescent cells and thus I would not see an increase---what do you think?
State the causes of diseases associated with bacilli, and include how the disease is transmitted (respiratory, stool, or soil contaimination)
At the same time, the gas loses 246 J of energy to the surroundings as heat. What is the change in the internal energy of the gas?
The compound phenylthiocarbamide (PTC) tastes very bitter to most persons. The inability to taste PTC is controlled by a single recessive gene. In the American white population, about 70% can taste PTC while 30% cannot (are non-tasters). Estimate ..
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A fish on the outside of a school swims inward, leaving other fish on the edge. These new "edge" fish then move inward and the cycle repeats.
The equilibrium potential for an ion species may be defined asthat potential required to keep the ions at a given concentrationand may be calculated from the nernst equation for that ionspecies. The concentration of K+ inside a squid axon is 400 m..
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Under what circumstances might using each of searches be useful even in your everyday life. Which search type is going to give you more reliable information.
Suppose that an organism exists in which crossing over does not occur, but that all other processes associated with meiosis occur normally.
How do you educate patients and families about infecton control measure in the community?
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