Reference no: EM133426541

Questions

1. Patients diagnosed with schizophrenia often report increased paranoia and auditory hallucinations. Chlorpromazine, a direct dopamine D2 receptor antagonist alleviates these symptoms. Discuss a potential alternative drug site, and whether the drug would need to be an agonist or antagonist, that you might expect to have a similar therapeutic effect compared to chlorpromazine. DO NOT GOOGLE DRUGS THAT TREAT THESE SYMPTOMS. Instead use what you have learned to identify a potential drug site target (not looking for a drug name).

Explain, the drug site and desired action of the drug.

2. Opioids have therapeutic relevance as a result of their analgesic (pain relieving) properties. Opioids exert analgesic effects by binding to and activating opioid receptors in the brain and spinal cord. At large doses, opioids can cause respiratory depression, and lead to death. Identify a potential drug site to counter the effects of opioids and explain how an agonist or antagonist would achieve that effect.