Pathways in disease development

Assignment Help Biology
Reference no: EM132456329

1. Write paragraphs describing the work presented. Include in your overview, some background on the topic and the goals and rationale of the study.

2. Write paragraphs describing the experimental design used to address the goal/problem and list the major results from each approach. Be sure to include the two key areas (proteomics results and central metabolism results) and how they connected the results from these two areas to make a complete story.

3. Answer the following questions.

1. Given what you know about regulation of central pathways, why did the authors not identify pathways that were required during infection in their proteomics experiments?

2. Could an enzyme/pathway be important during infection but not show an effect when it is knocked-out? Why?

3. What are the main findings in the paper? [hint: what does E. coli eat in the urinary tract?]

4. What is an auxotroph? How did the author demonstrate auxotrophic phenotypes in vitro? What did the in vivo results from the 2 auxotrophs tell us about the urinary tract environment and how did these data support the main findings of the paper?

Attachment:- Journal article for pathways assignment.rar

Reference no: EM132456329

Questions Cloud

How does the company improve service and quality : Spend money on new product Innovation and creation? How does the company improve service and quality (if at all)?
What is the effect of interest rates on the currency : What is the effect of interest rates on the currency of a nation?
Explain the differences between two types of validity : Explain the differences between two types of validity. Explain how experimenters control for subjects' and researchers' expectations.
What are the role that the product plays in society : Where does human factors engineering occur - design, manufacture, test and evaluation, etc.What are The role that the product plays in society
Pathways in disease development : Describing the experimental design used to address the goal/problem and list the major results from each approach.
Discuss the anthropometric design principle : Select a workstation where an anthropometric design principle was used or should be used. Characterize the user population. research a case study
Explain why the consumer utility is not maximised : Explain what MRS12 is (without referring to indifference curves.) Then, explain why the consumer's utility is not maximised at a point where MRS12 > p1/p2.
Explain the difference between errors and faults : Explain the difference between errors, faults, and failures. Give an example of an error that leads to a fault in the requirements; the design
NIT1204 Web Application and Server Management Assignment : NIT1204 Web Application and Server Management - Laboratory Assignment Help and Solution, Victoria University, Australia. Modify the Registration application

Reviews

Write a Review

Biology Questions & Answers

  What makes skin cells different from brain cells

Skin cells perform very different functions compared to brain cells. On the molecular level, what makes skin cells different from brain cells in the same organism

  Organisms are primary sources of antibiotics

In your own words. What kinds of organisms are primary sources of antibiotics? Also, how does misuse of antibiotics lead to somebacteria becoming resistant?

  Define the reversion and missense mutation

The E. coli gene lacYencodes a protein called lactose permease, Reversion, Intragenic suppressor, Intergenic suppressor, Missense mutation

  Why is timing not so critical with h2s readings

As mentioned in the theory, the fermentation readings with KIA must take place between 18 and 24 hours after inoculation.Why is timing not so critical with H2S readings?

  Process of chromatin remodeling in eukaryotes

Describe the process of chromatin remodeling in eukaryotes. Be sure to include any enzymes that are used in decondensation and condensation of DNA

  Is visual conspicuousness and toxicity is correlated

Is visual conspicuousness and toxicity is correlated? What type of control was used in this study? Why do you think they used this control?

  What is the size of the specimen

Earlier it was determined that your field size when using scanning power was 5mm, what is the size of the specimen?

  What are the electron acceptor and donor for fungi

Are fungi gram positive or gram negative? Explain based on the structure of its cellular envelope and explain the basis for your answer in terms of specific non-informational macromolecules.

  Bipotential progenitor of foregut endoderm

A pluripotent cell has been placed into specific culture situations to commit into an early bipotential progenitor of foregut endoderm. Further differentiation could send it to become a hepatocyte or a pancreatic cell.

  Write the structural formula for isoamyl alcohol

The hypothetical OxyA protein is a surface protein that may have a role in attachment to the surface of the intestinal epithelium but there is evidence that it has a role in invasion. Write the structural formula for isoamyl alcohol.

  Diagram the cross below to support

If a man with a red-colorblindness (a sex-linked trait) marries a normal woman, would you expect to see  trait expressed in their children.

  High-fiber whole-grain foods whenshe shops

What are some strategies that can help Erin identify high-fiber whole-grain foods whenshe shops?

Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd