Pathophysiology for fine inspiratory crackles

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What more can you add in the pathophysiology for fine inspiratory crackles?

Since there is lung tissue inflammation, neutrophils will migrate into the alveoli in response to an inflammatory stimulus. Neutrophil infiltration and proinflammatory cytokines lead to tissue edema, dysfunction, and subsequent destruction of pulmonary epithelium. This causes pulmonary capillaries' failure to absorb fluid leading to pulmonary edema. Crackles will then be heard upon auscultation as a sign of fluid in the lungs.

Reference no: EM133241491

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