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YOUR ASSIGNMENT THIS WEEK is to take the unknown sequence, go the the NCBI web page, and carry out a BLAST search. When you have located the GenBank record that matches this sequence exactly, go to the features table and locate the positions of the exons under the coding sequence (CDS) portion of the Features table (See "join" followed by nucleotide boundaries for each exon). How do the results of the GeneID and GENSCAN methods compare to the GenBank annotation? Go back to GENSCAN, and redo the analysis, lowering the probability value of correctly identifying exons (the suboptimal exon cutoff) until the initial exon is located. How low did you have to make the p value before the initial codon was located?
How many genotypes are produced by an autosomal gene with 5alleles? How many genotypes are produced by a X-linked gene with 5alleles?
the oxaloacetate-malate couple is less negative than the NAD_- NADH couple. How are these values compatible with the transfer of electrons from malate to NAD_ in the TCA cycle?
If you were to remove the ER retrieval signal (KDEL) from protein disulfide isomerase (PDI), which is normally a soluble resident of the ER lumen, where would you expect the modified PDI to be located? Why?
1 what is the preferable study group in mammalian testing of aging interventions mice or monkeys? why? 2 if you were
My research topic relates to a social issue and I like the idea of using the mixed methods approach. I intend to incorporate a combination of qualitative and quantitative data analysis. I'm trying to find out what the public sector is doing to hel..
Explain how the silent substitution rate (single base substitutions at sequence locations that do not affect the amino acid sequence) can be used to estimate the base mutation rate (µ).
Distinguish between those that are and are not membranous. Most are membranous. Explain the importance of membrane structure and function in the organization of living processes within cells.
"It is not the strongest of the species that survives, nor the most intelligent that survives. It is the one that is the most adaptable to change."
For several years the benefits of routine use of female hormone supplements by postmenopausal women have been debated.
Describe the order and linkage of the biochemical processes involved in ATP synthesis in mitochondria (glycolysis, TCA cycle,electron transport chain, proton pumping, ATP synthaseactivity)
Which hormones is responsible for the emotional states such as fear, anger and tension and a rise in blood pressure and heart rate?
How can coacervates be formed of phospholipids or polypeptides?
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