Oxygen binds to the oxy conformation of hemoglobin

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Reference no: EM13535002

In general, a ligandthat binds to only one conformation of an allosteric protein willstablize the bound conformation. Oxygen binds to the "oxy"conformation of hemoglobin, while carbon dioxide and small organcmolecule BPG bind to the "deoxy" conformation, each at differentsites. Which of the following statement is FALSE?
a) a high concentration of carbon dioxisde will stimulatebinding of BPG to hemoglobin
b) a high concentration of oxygen will stimulate dissoicationof BPG and carbon dioxide from hemoglobin
c) a high concentration of carbon dioxide will cause oxygen todissociate
d) in the presence of BPG, a lower concentration of carbondioxide is required to cuase dissociation of oxygen
e) a variant of hemoglobin that has a lower affinity for BPGwill bind to oxygen less tightly than normal hemoglobin int hepresence of the same level of BPG.

Reference no: EM13535002

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