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1:What types of evidence indicate that cancer arises from genetic changes?2: Discuss how is cancer different from most other types of genetic diseases?3:Outline Knudson's multistage theory of cancer and describe how it helps to explain unilateral and bilateral cases of retinoblastoma.4:What is haploinsufficiency? How might it affect cancer risk?5:What role do telomeres and telomerase play in cancer progression?6:Explain how chromosome deletions, inversions, and translations may cause cancer.7:What is genomic instability? Give some ways in which genomic instability mayarise.8:How is an epigenetic change different from a mutation?9:How is DNA methylation related to cancer?10:What is a Mendelian population? How is the gene pool of a Mendelian population usually described?11:What are the predictions given by the Hardy Weinberg law?12:What is random mating?13:Define inbreeding and briefly describe its effects on a population.14:Define inbreeding and briefly describe its effects on a population.15:What determines the allelic frequencies at mutational equilibrium?
Erythropoetin is available as a pharmacological drug treatment. Recently a well-known cyclist was accused of using erythropoietin.
It is commonly reported that up to 50 percent of a cell's energy budget is spent on protein synthesis. Think about the properties of two hypothetical genetic codes constructed with the four common nucleotides.
Think about a virus with a plus strand RNA genome 8 kb in length, which encodes eight proteins. Determine which of the following is a known mechanism for producing all eight proteins from this genome?
There are four main categories of molecules of life. Complete the table given by indicating, the name of each of the four categories of the molecules of life
Dialysis patients, who will have blood withdrawn, dialyzed, then replaced, are always weighed while they enter the facility and then weighed carefully before they leave. What is the most probable explanation for this requirement.
The main ecological imbalance on Earth is between the human species and the rest of Earth's biota. Determine two specific actions we could do to achieve a balance
Based on the dimensions of an alpha-helix, compute the range in width of the membrane? Discuss how many amino acids would be needed in an antiparallel beta strand to span the membrane?
A geneticist makes a cross between two homozygous strains of maize with three different mutations. For symbols, you can use a capital to indicate the dominant allele.
A zoologist is investigating a population of squirrels whose coat color is controlled by a single gene whose two alleles (B 1 & B 2 ) are codominant.
Through writing Henderson hasselback equation describe how pH is equal to pkA when exactly one half of lactic acid is dissociated into H+ and A- ions through titrating with 0.5M equivalents of NAOH.
Discuss and explain how you would calculate delta G for the reaction: glucose+6O2---> 6CO2+6H2O. If you were told that this reaction is highly exergonic.
Flask A includes yeast cells in glucose-minimal salts broth incubated at 30C with aeration. Flask B contains yeast cells in a glucose-minimal salt broth incubated at 30C in an anaerobic jar.
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