Origin for viral dna replication

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During replication of viral DNA of members of the Polyomaviridae, a pair of T antigen hexamers forms a preinitiation complex at the origin for viral DNA replication.

a) how do we know that DNA replication is bidirectional.

b) How many leading and lagging strands are there, and in what direction does synthesis of these strands occur?

Reference no: EM1384265

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Origin for viral dna replication : During replication of viral DNA of members of the Polyomaviridae, a pair of T antigen hexamers forms a preinitiation complex at the origin for viral DNA replication.
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