Olanzapine is used to treat schizophrenia-bipolar disorder

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Question

1. You are treating a patient with schizophrenia. The patient states that he does not want to take a medication that has really high extrapyramidal effects (EPS) side effects. Which of the following antipsychotic drugs has the highest rate of extrapyramidal effects?

a. Haloperidol

b. Aripiprazole

c. Olanzapine

d. Chlorpromazine

2. Clozapine is associated with milder extrapyramidal symptoms (EPS) than other antipsychotic medications. Which EPS side effect is most commonly observed with clozapine use?

a. Dystonia

b. Muscular rigidity

c. Bradyphrenia

d. Tremor

3. A 27-year-old male with a history of schizophrenia that was previously maintained on haloperidol is admitted to the hospital after calling the police because "the voices" were telling him to kill himself and his family. The patient's past medical history is significant for asthma and polycystic kidney disease. He also has developed a new parkinsonian tremor since he was last hospitalized. Given his decompensation and new tremor, the patient is switched to olanzapine (an atypical antipsychotic) to reduce his tremor. Which of the following is a possible side effect of olanzapine?

a. Tyramine crisis

b. Diabetic ketoacidosis

c. Weight loss

d. Worsening GFR

4. Olanzapine is used to treat schizophrenia and bipolar disorder. Which of the following statements about its used and side effects is true?

a. Diabetic ketoacidosis is common

b. EPS occurs more frequently than with risperidone

c. NSM with olanzapine presents with more motor symptoms than with typical antipsychotics.

d. Hyperlipidemia occurs frequently.

5. A 30-year-old male patient with a history of treatment-refractory schizophrenia presents for follow-up 1 week after being started on clozapine. The patient denies any adverse reactions or events since starting the medication. Labs done prior to starting him on the medication were WNL and included a CBC with differential, complete metabolic profile, fasting lipid panel, fasting glucose, and A1C. The patient's BP and BMI were also WNL and are largely unchanged at today's appointment. He seems to be tolerating the medication well, and no concerning findings are present on exam. What lab work, if any, should be rechecked at today's visit?

a. Complete metabolic profile

b. CBC with differential

c. Fasting lipid panel

d. Fasting glucose

Reference no: EM133506195

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