Oculocutaneous albinism is monogenic

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Reference no: EM133199181 , Length: 7 Pages

Oculocutaneous albinism (OCA) is a monogenic, recessive disorder caused by a mutation in the TYRgene. A is the symbol for the normal, dominant allele and a is the symbol for the recessive, albinism-causing allele. Another trait, freckles, is dominant in humans. F is the "freckles" allele and f is the "no-freckles" allele. Imagine that a woman with OCA who is heterozygous at the freckles locus has children with a man who is heterozygous at the freckles and is heterozygous at the TYR locus.

What are the genotypes and phenotypes of the woman and man?

What are the odds of their having a boy with OCA and freckles?

If the couple has two children, what are the odds that they are both girls with OCA, but without freckles?

Reference no: EM133199181

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