Reference no: EM132232938 , Length: word count:3000
Assignment - Master of Nutrition project
Need a mind map and literature review about Gut microbiota health does avoiding refined carbohydrate will help?
Summary of the key findings from my research including link between genetics and environmental triggers. Given significance of the problem there is an urgent need for further research into this field. Promising results to date from whole foods plant-based diet.
What do we know about the pathology of Parkinson's disease? Loss of dopaminergic-creating neurons in the substantia nigra.
What do we know about the causes of PD? Environmental (paraquat, metal ions) vs genetics. Where are the gaps in research in relation to cause?
What are the known risk factors?
The roles of oxidative stress and development of alpha-synuclein
Presenting symptoms - motor and non-motor manifestations and diagnostic criteria
What do we know about current treatments? Medications, alternative therapies including physical exercise, Speech and language therapy, mindfulness therapy
Issues with current treatments - benefits vs downfalls including levodopa therapy, MAOIs, deep brain stimulation
New approaches needed - emerging field of nutrition as medicine and role of diet in Parkinsons disease - in terms of improvement in constipation, gut microbiome relationship ?does parkinson's disease start in the gut? Current research relating to dairy intake and increase risk Parkinson's disease.
Role of antioxidants and PD progression/prevention
Evidence for caffeine, smoking (inverse relationship for latter)
Prodromal PD and possible reversal stage where dietary and environmental exposures can impact outcome
Evidence from Mediterranean diets and prodromal PD
Evidence of dairy consumption and increased PD
Evidence for protein-redistribution diet and motor performance
Fibre and increased bioavailability of levodopa
Leads us to the research gap - can a whole-foods plant based diet improve symptoms of PD?
Attachment:- Project Assignment File.rar