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A particular district of your nation had a higher incidence rate for polio last year compared to the rest of the country. That region has been traditionally been resistant to vaccination efforts. You have commissioned a case-control study for the village to evaluate the situation after a recent outbreak of the disease in the area to measure vaccination status among the 63 poliomyelitis cases and 126 age- and neighborhood-matched controls. Cases were found to be under-vaccinated through routine immunization (matched odds ratio [MOR], 0.3; 95% confidence interval [CI],0.1-0.5).a. What do the odds ratio and given confidence interval indicate? (3 points)The matched odds ratio 0.3 indicated that vaccination was associated with 70%decrease in the risk of poliomyelitis and the 95% confidence interval [0.1 - 0.5]indicated that we are 95% confident that vaccination was associated with [50% to90%] decrease in the risk of poliomyelitis. B. How was the odds ratio calculated? (3 points)There are 4 possible outcomes with respect to the matched pair:⇒ Case exposed; Control exposed⇒ Case exposed; Control not exposed⇒ Case not exposed; control exposed⇒ Case not exposed; control not exposed Let u is the number of pairs in which "Case exposed; Control not exposed" and v is the number of pairs in which "Case not exposed; control exposed".Odds Ratio = u/v = 0.3
Elaborate on u and v in my calculation; where would these fit on a 2x2 table?; I must explain the statistics to an understandable level in a press release.
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