Mutation of the dvl1 gene

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Reference no: EM1385806

Question: A patient has been brought to you who is thought to have a mutation of the DVL1 gene, a human homologue of the Drosophila Disheveled gene. The hypothesis is that this mutation eliminates the ability of the DVL1 protein to bind to the human equivalent of Axin in one tissue. What effect would you predict this mutation has on transcription of the target genes in this tissue? Describe your answer to receive full credit.

Reference no: EM1385806

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