Reference no: EM133455960

Question

1. Brainstorm and list as many features as possible that make a typical mucous membrane an effective barrier/protective barrier- use the lining of the upper airway as an example.

2. Using the following list of terms, "map out" how fever is generated, Start your map with the presence of an "unfriendly" bacterium in the tissues. hypothalamus, macrophage, prostaglandins, pyrogen, IL-1, general circulation, phagocytosis.

3. A. Which of our cell types are most likely to have TLRs? (Toll Like Receptors)

B. Give a few examples of what can bind to and activate TLRs?

C. What happens as a consequence of this binding?

4. List the 3 "pathways" to activate complement.

5. Think about a B cell interacting with a CD4+ (T helper) cell, during activation of a B cell.

Explain the membrane proteins/receptors/peptides involved when these two cells form an "immunological synapse".

6. What is B7?

A. Which cell type(s) expresses B7?

B. When is it expressed/What causes it to be expressed?

C. What does B7 bind to?

D. What does B7 "signify"? What does it mean?