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You are attempting to modify an existing antimicrobial drug to treat intestinal bacterial infections. The drug has numerous unwanted side effects when it reaches the bloodstream, so you want to enhance the availability of the drug in the GI tract, but limit its appearance in the bloodstream. Which of the following would have the desired effect? Select all that apply.
A. Design the drug so its metabolism in the liver is reduced
B. Reduce the binding of the drug to serum albumin
C. Increase the molecular weight of the drug
D. Modify the drug so it is charged/more polar at pH <3.0
E. Modify the drug so it is uncharged at pH <3.0
q1. what is the biodiversity?what are some of the most biodiverse ecosystems on the globe and how are humans impacting
Biological basis.Describe the technology. Discuss what it accomplishes. Elaborate on the scientific principles that make this technology possible. Your goal in this section of the paper is to show the instructor that you understand the underlying sci..
Anika's cortisol secretion level falls to normal after the medication, but Bonnie's cortisol secretion remains elevated. Which patient has primary hypercortisolism, also called Cushing's syndrome?
Explore Endocrine, Circulatory, and Respiratory Systems: Review the background information and animation to complete your report
Did this series of questions correctly organize each organism? Why or why not? What additional questions would you ask to further categorize the items within the kingdoms (Hint: think about other organisms in the kingdom and what makes them differe..
q1. two pigs whose tails are accurately 25 cm in length are bred over 10 years and they produce 96 piglets with the
The decomposition of dead plants and animals is necessary to maintain an equilibrium in an ecosystem. Explain this statement in terms of the carbon cycle
hydrogen bonds may be important in what other biological macromolecules?
please answer the quesiton in complete and shortresponse.
Think about the following three mice: a gray male, a gray female, and a tan female. When the male mated with the gray female, all the offspring were gray.
Discuss how much energy do methanogenic bacteria get from using glucose and hydrogen to form methane and water as the products?
When a tropical moth is touched on the thorax it lifts its forewings up abruptly, exposing its brightly coloured hind-wings. What causes the moth to behave this way? What significance can we attach to the fact that the verbal ability scores of ado..
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