Reference no: EM133092098

CHT214 Biocatalysis I: Modern Approaches to Biocatalysts

Knowing(these are things that students will need to be able to do to pass the module)
Question:  Compare and contrast the advantages and disadvantages of biocatalysis relative to conventional chemical catalysis.
Question:  Describe methods for recombinant protein production and purification.
Question:  Understand the molecular basis of enzyme catalysis and discuss how this information can be used to engineer existing enzymes so as to extend their range of substrates and other physical properties, such as thermal stability.
Question:  Describe how biocatalysts are used in industrially relevant applications.

Acting(performance in this area will enable students to obtain more than a basic pass)
Question:  Propose an appropriate strategy for production of a given enzyme.
Question:  Propose biocatalytic methods to obtain small molecules with high stereochemical control.
Question:  Understand the technical problems, such as co-factor regeneration, associated with using enzymes outside of cells.

Being(performance in this area will enable students to obtain more than a basic pass)
Question:  Formulate strategies for the preparation of "engineered" biocatalysts in the laboratory.
Question:  Explain the use of biocatalysts for asymmetric production of fine chemicals.