Reference no: EM1389736

1. Determine which of the following mutations is more likely to produce a severe rather than mild phenotypic consequence(s)?
Synonymous mutations
Nonsense mutations
Missense mutations
None of the above
All of the above
2. Shown below is a list of statements (a-k) and types of mutations (1-8). On the blank line following each mutation, write the letter(s) of all statements that apply to that type of mutation. Hint: Each statement may be used more than once and each type of mutation may have more than one correct statement.
a) A mutation that changes UUA to UUG
b) A mutation that gives methionine instead of leucine
c) Created by the addition of a nucleotide to a coding region
d) A stop codon is read as an amino acid
e) A chemically similar amino acid is replaced by the mutation
f) A mutation that changes CCU to ACU
g) Deleting a nucleotide in a coding region gives this type of mutation
h) Mutation does not alter the peptide
i) A mutation changing UAU to UAG
j) Premature termination codon is responsible for this mutation
k) A chemically different amino acid is replaced by the mutation
1) Missense mutation __________
2) Silent mutation __________
4) Frameshift mutation __________
5) Nonsense mutation __________
6) Synonymous mutation __________
7) Suppressor mutation __________
3. Salvador Luria and Max Delbruck designed the flunctuation experiment to show that______________
resistant cells were produced by phage infection
resistant cells were selected by phage infection
phage infection did not have any effect on resistant cells
resistance cells were produced by environmental mutagens
none of the above
4. The FMR-1 gene undergoes ________________ to produce susceptibility to fragile X syndrome
differential expression
excessive phosphorylation
tri-nucleotide repeat expansion
transversion mutation
non-synonymous mutation
5. Which of the following could be examples of spontaneous mutations?
a) Deamination
b) Trinucleotide expansion
c) Dimerization of pyrimidine bases
d) Depurination
e) Oxidation