Reference no: EM133296878

Questions

1. Treatment with a mutagen caused a single base pair change within a gene, altering a single codon in the mRNA. Which of the following amino acid substitution is consistent with this information? (show work and explanation please)

a) Ala to Thr

b) His to Glu

c) Met to Glu

d) Phe to Lys

e) Lys to Ala

2. Upon retroviral infection, which of the following would accumulate by the addition of a drug that inhibits integrase

a) Viral particles outside the cell

b) Double strand viral DNA

c) Double strand viral RNA

d) Multiple copies of the viral genome in the host genome

e) Viral packaging proteins

3. If DUE was deleted the E.Coli origin of replication, which would likely happen?

a) Replication would be blocked during the elongation stage

b) The leading strand would replicate, but not the lagging strand

c) The double strands would not unwind

d) DNA polymerase would synthesize the DNA in a 3' to 5' direction

e) DNA would not bind the origin.

4. A mechanism of gene regulation in prokaryotes that does not exist in eukaryotes involves:

a) coupling transcription with mRNA capping

b) coupling transcription with mRNA splicing

c) coupling transcription with polyadenylation

d) coupling transcription with translation

e) coupling translation with post-translational modifications

5. A new drug inhibits a Type I hormone receptor from binding to hormone. Where will the receptor will be located in the cell upon drug treatment?

a) in the nucleus bound to DNA

b) in the cytoplasm bound by a chaperone

c) in the cytoplasm bound to a long non-coding RNA

d) in the cytoplasm bound by a co-repressor

e) in the nucleus bound by a transcriptional co-repressor