Major routes of administration for beta

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The major routes of administration for beta-2 agonists include metered dosed-inhalers, nebulizers, dry powder inhalers, orally, subcutaneously, or intravenously. The preferred route of administration for beta-2 agonists in the treatment of asthma and COPD is through inhalation. Inhalation localizes the drug to the lung tissue, concentrating the therapeutic effect on the airway smooth muscles while minimizing the distribution of the drug to the systemic circulation. There has been no correlation between the therapeutic effect of inhaled beta-2 agonists and the peak plasma levels of the beta-2 agonist. Less frequently, beta-2 agonists are given orally, which have been shown to cause an increase in systemic side effects. The tocolytic terbutaline can also be given IV, IM, or orally. The different types of inhalers techniques, include metered-dose, dry powder and soft mist inhalers. They usually treat asthma and COPD but providers may prescribe them for other conditions. Bronchodilators and corticosteroids are common inhaled medications.

Reference no: EM133724673

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