Solution-Kinetics of the metabolism of the drug

Kinetics of the metabolism of the drug

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Reference no: EM131910970

Sotalol is a drug with beta-blocker and antiarrhythmic action. The kinetics of the metabolism of the drug were followed by concentration of the remaining non-metabolised sotalol at different times as tabulated in the table below.

Table: Concentration of non-metabolised sotalol as a function of time.

Time/ h : 0 : 10 : 20 : 30 : 40 : 50 : 60 :

[ sotalol] / nM: 2.00: 1.26: 0.80: 0.50: 0.32: 0.20: 0.13:

a) Determine the order of reaction using plot and discussion.

b) Calculate the rat of constant showing all working.

c) Calculate the half-life graphically and analytically (numerically ).

Reference no: EM131910970

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Kinetics of the metabolism of the drug

Reference no: EM131910970

Reference no: EM131910970

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