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Twelve patients having high albumin content in their blood were treated with a medicine. Their blood content of albumin was measured before and after treat- ment. The measured values are shown in the table.
Blood Content of Albumina a Values given in grams per 100 ml.
Patient
Before Treatment
After Treatment
1
5.02
4.66
2
5.08
5.15
3
4.75
4.30
4
5.25
5.07
5
4.80
5.38
6
5.77
5.10
7
4.85
8
5.09
4.91
9
6.05
5.22
10
4.77
4.50
11
12
5.24
4.56
Is the effect of the medicine significant at the 5 percent level?
• Use the sign test.
• Use the signed rank test.
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