Is it possible to determine from the pedigree

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Is it possible to determine from the pedigree when the PSEN1 gene mutation first occurred? If so, how? If not, why not?

Reference no: EM133663375

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Is it possible to determine from the pedigree : Is it possible to determine from the pedigree when the PSEN1 gene mutation first occurred? If so, how? If not, why not?
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