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PICO question using the PICO format guide: Population: Children under the age of five. Intervention: Early intervention programs. Comparison: No early intervention programs. Outcome: Improved developmental outcomes. PICO question: In children under the age of five, does early intervention programs compared to no early intervention programs, lead to improved developmental outcomes? The PICO framework is a widely recognized and accepted approach to developing clinical research questions. However, there may be situations where using a different framework would be more appropriate. For example, if the focus of the research question is more on the patient experience rather than a clinical outcome, the PICOT framework may be more appropriate. Internal evidence that could justify the decision to adopt a different framework may include qualitative data from patient surveys or focus groups, which can provide insight into patient perspectives and experiences. Additionally, if there is existing literature that has used a different framework to address similar research questions, this could provide further justification for using a different framework. For example, if the research question is focused on understanding the impact of early intervention programs on caregiver stress, the CARE framework may be more appropriate: Population: Caregivers of children under the age of five.
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