Interacting genetic and environmental variables

Assignment Help Biology

Reference no: EM1384534

Question: Most human obesity does not follow Mendelian inheritance patterns, because body fat content is determined by a number of interacting genetic and environmental variables. Insights into how specific genes function to regulate body fat content have come from studies of mutant, obese mice. In one mutant strain, tubby (tub), obesity is inherited as a recessive trait. A comparison of the DNA sequence of the tub+ (wild-type allele, or the nonmutated allele) and tub alleles has revealed a single base-pair change: within the transcribed region, a 5' G-C base paur has been mutated to a T-A base pair. The mutation causes an alteration of the initial 5' base of the first intron. Therefore in the homozygous tub/tub mutant, a longer transcript is found. Propose a molecular based explanation for how a single base changes causes a nonfunctional gene product to be product, why a longer transcript is found in the tub/tub mutants.

Reference no: EM1384534

Questions Cloud

Find the flow speed of medicine through the needle : A 1 mL syringe has an inner diameter of 4.0 mm, a needle inner diameter of 0.220 mm, and a plunger pad diameter (where you place your finger) of 1.20cm.

Prepare gross pay and net pay functions for valid user name : Prepare gross pay and net pay functions, and give user input validation to check for valid user name. Hours worked is between 0 and 80 hours, and hourly wage is between $8.95 and $50.

Two immiscible fluids are in contact : Two immiscible fluids are in contact. Fluid I is denser and is also well mixed. The concentration of species a is cao everywhere within this fluid and the temperature in fluid I is held constant at To.

How many kanban card sets are needed : Due to variations in processing times, management has decided to keep 20 percent of the needed inventory as safety stock. How many kanban card sets are needed?

Interacting genetic and environmental variables : Most human obesity does not follow Mendelian inheritance patterns, because body fat content is estimated through a number of interacting genetic and environmental variables.

Explain how are the functions of management evolving : Explain how are the functions of management evolving in today's business environment? Be sure to format your response in APA and provide two APA formatted references.

Design strategy for dealing : Develop a 10- to 15-slide presentation which uses a public health approach to design a strategy for dealing with the scenario above. Write a 1,750- to 2,850-word paper to go with the slide presentation on the above scenario.

Are you concerned that this might be a crisis situation : Are you concerned that this might be a crisis situation-akin to an employee going "postal" in the workplace-waiting to happen? If so, what would you do? Why?

Define the s-t cut on node capacitated network : How would one define the s-t cut on node capacitated network as opposed to the edge capacitated network, and how would one illustrate that analogue.

User Account

All Pages