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Question: Most human obesity does not follow Mendelian inheritance patterns, because body fat content is determined by a number of interacting genetic and environmental variables. Insights into how specific genes function to regulate body fat content have come from studies of mutant, obese mice. In one mutant strain, tubby (tub), obesity is inherited as a recessive trait. A comparison of the DNA sequence of the tub+ (wild-type allele, or the nonmutated allele) and tub alleles has revealed a single base-pair change: within the transcribed region, a 5' G-C base paur has been mutated to a T-A base pair. The mutation causes an alteration of the initial 5' base of the first intron. Therefore in the homozygous tub/tub mutant, a longer transcript is found. Propose a molecular based explanation for how a single base changes causes a nonfunctional gene product to be product, why a longer transcript is found in the tub/tub mutants.
Describe how EDTA promotes the dissociation of animal cell tissue. How various genotypic and phenotypic combinations are possible in the offspring of a brown-eyed, red-haired, taster man with AB blood group (Bb rr Tt AB) married to the blue-eyed, non..
At what stage of the cell cycle are the chromosomes satisfactorily condensed that they FIRST become visible under the light microscope.
explain some of the bioethical concerns related to screening for genetic diseases.
Explain how the ankylosing spondylitie is diagnosed and what are the diseases, which have symptoms that are similar to AS. Explain and list the organs which are affected by the Ankylosing Spondylitis.
Explain why carcinomas are more common than sarcomas? Describe briefly your favourite new term or concept from this class.
You are designing a new single-celled organism. Discuss the problems of size, getting molecules like nutrients and wastes in and out, temperature, energy and replication of genetic materials.
What everyday tasks do you think would become more challenging if Homo sapiens were full- time quadrupeds in the place of full-time bipeds? Explain the answers in details.
Discuss why is the ovulate cone of a pine designed to be so much more durable than the staminate cone? Find the advantage of having seeds rather than spores?
Clostridium and Streptococcus are both catalase-negative. Streptococcus grows by fermentation. Why is Clostridium killed by oxygen, whereas Streptococcus is not.
Evaluate and contrast the major muscle groups of the upper and lower limbs and relate their similarities and differences to their function.
The bacteria are allowed to grow overnight and are streaked on a plate using the technique that produces isolated colonies that are clones of the original. Samples of these colonies are then grown in four different media: nutrient broth plus ampicill..
Increase the ratio of succinate to malonic acid reduces the inhibitory effect of malonic acid. Which is correct answer. What are the genotypes of the albino's parents.
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