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Hypertension in women planning for pregnancy Poorly-controlled hypertension in the first trimester significantly increases maternal and fetal morbidity and mortality. The majority of guidelines and clinical trials focus on the management and treatments for hypertension during pregnancy and breast-feeding, while limited evidence could be applied to the management for hypertension before pregnancy. In this review, we summarized the existing guidelines and treatments of pre-pregnancy treatment of hypertension. Methyldopa and labetalol are considered the first choice, but angiotensin-converting enzyme (ACE) inhibitors and angiotensin receptor blockers (ARBs) need to be withdrawn if a hypertensive woman wishes to become pregnant. In women with chronic hypertension, it is very important to make an assessment before conception to exclude secondary causes of hypertension, evaluate their hypertensive control to ensure that it is optimal, discuss 1 Step-by-step explanation Generated by AI When managing hypertension in a woman of reproductive age, it is crucial to consider both the safety of the medications during potential pregnancy and the overall health of the woman. Here are the key points: Medications: First-Line Medications: Methyldopa: This medication is often recommended due to its safety profile during pregnancy. Labetalol: Another preferred option, labetalol is effective and considered safe for use during pregnancy.
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