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In a clinical trial of a drug used to help subjects stop smoking, 812 subjects were treated with 1 mg doses of the drug. That group consisted of 49 subjects who experienced nausea. The probability of nausea for subjects not receiving the treatment was 0.0142.
a) Assuming that the drug has no effect, so that the probability of nausea was 0.0142, find the mean and standard deviation for the numbers of people in groups of 812 that can be expected to experience nausea.
Based on the result from part (a), is it unusual to find that among 812 people, there are 49 who experience nausea? Why or why not?
Based on the preceding results, does nausea appear to be an adverse reaction that should be of concern to those who use the drug?
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This question is asking for speculation about the possible results of a study if we change the size of the population. It all depends on unknowns such as how representative the 100 adults are of the population.
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