Impacting the excretion of drugs and metabolites

Reference no: EM133718491

Question

Additionally, renal function in children is less efficient compared to adults, impacting the excretion of drugs and their metabolites (McCuistion et al., 2023). These developmental differences necessitate careful consideration of dosing regimens in pediatric patients to achieve therapeutic effectiveness while minimizing the risk of adverse effects. For instance, antibiotics like gentamicin require precise weight-based dosing adjustments in children to account for variations in renal function and body composition, ensuring that therapeutic levels are achieved safely and effectively (Hollander et al., 2023).

Reference no: EM133718491

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