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Q1. For this assignment you will be provided with 2 clinical research questions on sample size and one published paper to determine the power of the primary outcome measure reported in the study.
Q2. A survey is being planned to estimate the prevalence of secondary infertility amongst couples aged 20-45. The investigators expect the prevalence to be 10%, and would like to estimate it to within 5% of the true value (with 90% confidence). How many couples are required?
Q3. A previous small study was investigating the total cost of 10 specific items of fruits and vegetables which were sold in 3 supermarkets compared to that were sold in 3 local corner shops. On average the total cost of 10 specific items of fruits and vegetables which were sold in local corner shops was £5.50. It was suggested that the total cost of those fruits and vegetables which were sold in supermarkets was 50% cheaper than the local corner shops, with a common standard deviation of 1.65. Use the PS power calculator to find out how many supermarkets and local corner shops are required (assume equal group) , if we are going to conduct a similar study to investigate the difference in cost of this size, with 90% power and using a 1% significance level?Q4. Read the paper titled "Plasma Fetuin -A is associated with the Severity and Cognitive Impairment in Mild to moderate Alzheimer's Disease" Edward R. Smith, RaminNilforooshan et al. Journal of Alzheimer's disease, 2010.
Identify the primary outcome measure and calculate using PS-sample size program to determine the power of the primary outcome measure, stating clearly the measures that were used to arrive at the result. Use 0.05 as type I error for the calculation. Also comment on the value of the difference whether this was clinically relevant or not.
Do these results suggest that the different therapies have different effects on mental health? (Use the .05 level.) a. Use the five steps of hypothesis testing.
q1. a pistachio rancher buys a new fertilizer system that is supposed to increase the yield per acre. she uses the
A company is interested in estimating the mean number of days of sick leave taken by its employees. The firm's statistician randomly selects 100 personnel files and notes the number of sick days taken by each employee.
Compare the two forecasts computed in (a) and (b), using MAD. Which one should the dealer use for January of the next year?
School seniors in his random sample, 159 believe that "getting rich" is an important goal. Can he conclude, at the 0.05 level of significance, that the proportion has indeed changed?
How much should a healthy shetland pony weigh? Let X be the age of the ponies in months and y be the average weight of the ponies, in kilograms.
Test the hypothesis that more than 60 percent of the U.S. senators (of a total 100 senators) favor the president's economic plan, if a sample of 40 showed that 22 favor the plan (use alpha = .05).
Find the combination of Model Alpha and Model Beta that maximizes the firm profit. What is firm's profit at this profit mix and shows the combinations of Model Alpha
A 2007 study reported in Science magazine stated that fifth-grade teachers scored a mean of 3.4 (out of 7) points for "providing evaluative feedback to students on their work." Assume that the sample size was 36 and the sample standard deviation w..
Suppose 5.9% of certain population use public transportation to get to work. You randomly select 380 workers and ask them if they use public transportation to get to work.
Why might driver be tempted not to use seat belt "just on this trip"?
The mayor of a small town would like to know whether a local bond issue is likely to pass or not. He mails a survey to 500 randomly selected voters.
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