How would these differences be manifested clinically

Reference no: EM133470966

Case:

An adult patient with a chronic myelogenous leukemia sits down with you to discuss his questions and concerns about his upcoming bone marrow transplant. He has already received some educational materials and participated in a family conference during which health team members described the procedure and potential complications. He has been told that he has a risk of graft rejection or graft versus host disease (GVHD), but he does not understand the distinction (Chapter 12, Learning Objectives 1, 2, 10, 11).

Question 1: What are the similarities between graft versus host disease and graft rejection?

Question 2: What are the pathophysiologic differences between graft versus host disease and graft rejection?

Question 3: How would these differences be manifested clinically?

Question 4: Studies have shown a protective effect of mild to moderate GVHD in cancer patients who have had a bone marrow transplant. Based on your understanding, can you explain these findings?

Reference no: EM133470966

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