How will mutation affect relation in reaction nd concentrion

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An enzyme that follows the MWC (also known as the concerted model) model for allostery has a T/R ratio of 300 in the absence of substrate. Suppose that a mutation were to reverse that ratio(T/R= 1/300= 3.3 x 10^-3). How would this mutation affect the relation between the rate of the reaction and the substrate concentration, i.e. what would the initial velocity vs. [S] plot look like and why?

Reference no: EM13326619

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