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Signal transduction and cell cycle regulation intersect in a discussion of tumor formation. Pick one signal transduction pathway we have discussed. Describe the steps involved and how the pathway leads to cell cycle activation. Discuss three potential mutations of proteins along this pathway that could lead to tumor formation. Indicate whether such mutations would be expected to be gain of function or loss of function.
Why might replacing an arginine with a histadine result in a defective protein?
What growth pattern would be expected if a plant contained a greater number of cell receptors for auxins? An excess of cytokinin receptors?
Consider the tetrahybrid cross between AaBbCCDD and AaBbCcDd. Assume that it is a dominant/recessive system and all genes are unlinked. What proportions of the offspring will have the recessive Phenotype for all four characteristics?
If a cell were treated with an inhibitor that would cause microtubules to fall apart, which of the following would NOT be affected?
Microtubules can be formed in vitro from tubulin that is bound to GTP analogues that (unlike GTP) cannot be hydrolyzed. What properties would you expect these microtubules to possess?
In dogs, dark coat (D) is dominant over albino (d) and short hair (S) is dominant over long hair (s). After crossing dogs with dark and short hair with albino dogs with long hair, in F2 a breeder got 89 dogs with dark and short hair, 31 dark, long..
At which stop codons would the mutant tRNAglu be able to suppress translational termination? (assume that G-U base pairing is possible at the wobble position)
Studies on the global climate cycle have revealed a %u201Cmissing%u201D carbon sink (i.e., carbon being taken from the atmosphere and put into the biosphere) of approximately 3 GT/year (thought to be an underestimate of the size of the photosynthe..
Which is MOST important in bone resorption.
Distinguish indeterminate from determinate growth. If you were a redwood tree and redwood trees could be vegocentric in the same way that humans can be anthropocentric, what would you think of as "normal"?
A scientist was working on "specific toxic material" and he had identified that because of this toxin, cytoplasmic levels of cAMP was increased and this elevated levels disturbed overall homeostasis of living system
How do diffusion gradients of morphogens affect development?
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