How the drug might have neutralized the fungal hyphae

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Matt was not in good shape, and it had nothing to with the time spent at the gym. It had to do with the ball of fungus in his right lung. That fungal sphere, Aspergilloma had started as a single spore of ascomycete fungus called Aspergillus. The mold had formed the mass of fungal hyphae that was invading the airways of his lung and slowly killing him. Such bronchopulmonary Aspergillus is a rare but increasingly frequent pathogen of the immunocompromised.Besides experiencing difficulty in breathing, fever and chest pain, Matt most hated coughing up wads of bloody mucous. His disease had invaded his blood and was now progressing to his brain. Soon it might lead to paralysis. Matt spent 4 weeks at the hospital and thankfully a new antifungal drug, Voriconazole brought Matt back to life.

How could a microbiologist determine that the fungus infecting Matt is an Aspergillus not any other fungus? Through research look up how antifungal drugs work and explain how the drug might have neutralized the fungal hyphae.

 

Reference no: EM133515232

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