How the clients disease might affect pharmacokinetics

Reference no: EM133722155

Problem

You are changing the administration route of a medication that has a high first-pass effect from IV to PO; what would you expect the oral dose to be in relation to the IV dose? Your client with end stage liver disease is being prescribed a drug that is highly protein bound. Which statement best describes how this client's disease might affect pharmacokinetics?

Reference no: EM133722155

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