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How rituximab can kill the cells that it binds

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Reference no: EM132742552

You are a medical fellow in the Department of Hematology/Oncology at Memorial Sloan-Kettering Cancer. One of your patients has been diagnosed with lymphoma, specifically Non-Hodgkin's Lymphoma (NHL). Lymphoma is cancer that begins in cells of the lymph system. One type of lymphoma is Non-Hodgkin's lymphoma (NHL). There are many different types of NHL that form from different types of white blood cells (B-cells, T-cells, NK cells). Most types of NHL form from B-cells. One of the more advanced treatment for NHL in your arsenal is the use of the monoclonal antibody, Rituximab. Rituximab targets CD20 on B cells. CD20 is a signature B-cell differentiation antigen that is present through most stages of B-cell development and is ultimately lost in plasma cells.

a. Explain two way how Rituximab can kill the cells that it binds to.

b. Are there any concerns about giving this immunotherapy? Explain.

Reference no: EM132742552

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