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1. Since lactate is a "dead end" product of metabolism in the sense that its sole fate is to be converted into pyruvate, what is the purpose of its formation?
2. The molecule 2, 4 -dinitrophenol (DNP) is an uncoupler of oxidative phosphorylation. For a short period of time, it was prescribed clinically as a pill for weight reduction (against the advice of ssientists). Explain the basis for its ability to cause weight loss.
3. Consider the following reactions, which are two consecutive steps in the cyclic, multistep metabolic pathway referred to as the Kreb's cycle. The first reaction, which is not thermodynamically spontaneous, immediately precedes the second reaction, which occurs spontaneously. The two reactions are catalyzed by two independent enzymes.
L-malate + NAD plus<----> oxaloacetate + NADH + H plus +7(delta G knot --KJ/mol)Acetyl - CoA + oxaloacetate <----------> citrate +CoA -8( " " " " " )
How can the initial reaction occur in this pathway with such a high positive standard free energy?
Select appropriate symbols for the alleles of the height and flower colour genes. List phenotypes and predicted ratios for the F2 generation.
Suppose after washing your hands, you leave ten bacterial cells on the new bar of soap. You next decide to do a plate count of the soap after it is left in the soap dish for 24 hours. You dilute 1g of the soap 1:10 and plate it on a standard plate co..
He was puzzled, combative, and he refuses to drink any water or any liquid. He lived on Oct. 7th, 1849. While said to the man's name, the student thought "Nevermore!" What was his diagnosis.
Metabolism uses various ways to ensure that 2 opposing pathways do not occur at the equal time. For the following pair of pathways list 2 ways (different cell location, allosteric effector, covalent modification, different intermediate, different ..
The heart is in the middle thoracic cavity, known as the ______. The membrane around the heart is the ______. The thick muscular wall of the heart is the ______. The smooth inner lining of the heart is the ______.
Genistein and staurosporin are potent kinase inhibitors. Are genistein ans staurosporin more likely to have an effect in the signal cascade of G-prrotein related or enzyme linked (RTK) receptors.
What are the primary differences between animal cells, plant cells, and bacteria cells? What chacteristics do they share.
How could you explain the occurrence of birth defects (caused by altered genes) in children and grandchildren of WWII atomic bomb victims, while the victims themselves were only mildly affected.
Assume you performed a gram stain on a sample from a pure culture of bacteria and observed a field of red and purple cocci. Adjacent cell were not always the similar colour. What do you conclude.
Suppose that transgenic organisms can be developed to speed nitrogen fixation. How might use of these organisms affect ecosystem.
Batch and continuous sterilisation
Atherosclerosis is the progressive disease of blood vessels that is responsible for millions of death each year. Explain disease process, noting the involvement of specific cell/tissue types and molecules.
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