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How many participants must be enrolled in the study

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A clinical trial is being planned to investigate the effect of a new experiment drug designed to reduce total serum cholesterol. Investigators will enroll participants with total cholesterol levels between 200-240, they will be randomized to receive the new drug or a placebo and followed for 2 months, and the total cholesterol will be measured. Investigators plan to run a test of hypothesis and want 80% power to detect a difference of 10 patients in Mean total cholesterol levels between groups. How many participants must be enrolled in the study? Assume that the standard deviation of total cholesterol is 18.5.

Reference no: EM13243737

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