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Cystic fibrosis is an autosomal recessive disease in which the cystic fibrosis transmembrane conductance regulator (CFTR) protein is abnormal. The transcribed portion of the cystic fibrosis gene spans about 250,000 base pairs of DNA. The CFTR protein, with 1,480 amino acids, is translated from an mRNA of about 6,500 bases. The most common mutation in this gene results in a protein that is missing a phenylalanine at position 508 (?F508).
1. How many nucleotides are translated in the CFTR protein?
2. With regard to the ?F508 mutation: At the DNA level, what specific alteration has occurred? (3 points)
3. Show the exact change in sequence of #2
In Staphylococcus epidermidis, bacillus subtilis and escherichia coli, which one has gram- positive, which one has gram-negative? Also, which organism is the biggest? Which one is the least.
Under certain conditions, the rate of mutation of a particular gene may be determines in humans. What properties of the mutation would favour the most direct determination of mutation rate in humans? Write three points.
what type of digestive system does the earthworm have? describe the function of crop and gizzard.
If a translocation heterozygote is semisterile, why is a homozygote for the same translocation fully fertile?
Explain the events required for the activation of T lymphocytes. How can controlling the receptors involved can be used as experimental treatments for autoimmune diseases?
Which regions produce the most fish? 1. The Indian Ocean 2. The Atlantic Ocean 3. The Atlantic and The Indian Ocean 4. The Pacific Ocean 5. None of the above
Two viral genomes are sequenced, and the following percentages of nucleotides are identified, Detemine the structure of DNA in genome 1?
Which type of neural activity, action potentials, or synaptic potentials, produces the EEG? Explain your answer. Speculate as to why the EEG may be influenced by hyperventilation.
Alice expresses guilt that she may have caused Lauren's autism disorder, and is also concerned that it might occur again in future offspring. What would you advise her in terms of preventive actions, available testing, and reproduction options whe..
Mendel crossed crossed true-breeding yellow wrinkled (GGww) pea plants to true-breeding green plump (ggWW) pea plants in the P generation. The F1 plants were self crossed. If he only counted 10 plants in the F2 generation, what is the probability ..
Explain how tail length is inherited. Indicate how many gene pairs are at work and designate the genotypes of the two parents and lf the F1 offspring.
Gel filtration column was calibrated with blue dextran, its elution volume found to be 17.4 mL. Then, unknown protein and BSA were ran through the same column and eluted in 43 mL and thirty-six mL correspondingly.
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