How many different gene marker combinations are possible

Assignment Help Basic Statistics

Reference no: EM131404482

Detecting quantitative traits in genes. In gene therapy, it is important to know the location of a gene for a disease on the genome (genetic map). Although many genes yield a specific trait (e.g., disease or not), others cannot be categorized since they are quantitative in nature (e.g., extent of disease).

Researchers at the University of North Carolina at Wilmington developed statistical models that link quantitative genetic traits to locations on the genome (Chance, Summer 2006). The extent of a certain disease is determined by the absence (A) or presence (B) of a gene marker at each of two locations, L1 and L2 on the genome. For example, AA represents absence of the marker at both locations whereas AB represents absence at location L1 but presence at location L2.

(a) How many different gene marker combinations are possible at the two locations? List them.

(b) Using dummy variables, write a model for extent of the disease, y, as a function of gene marker combination

(d) Give the null hypothesis for testing whether the overall model, part b, is statistically useful for predicting extent of the disease, y.

Reference no: EM131404482

Questions Cloud

Summarize the reasons why senate bill 618 was implemented : Summarize the reasons why Senate Bill 618 was implemented in California, the program's design, and why it was different from traditional prison programming..How successful or unsuccessful was this program in reducing recidivism and helping offende..

Write the equation of the model : Predicting oil spill evaporation. - Write the equation of the model.- Identify the terms in the model that allow for curvilinear relationships.

Conduct the global f test for model utility : Fit the model to the data and give the least squares prediction equation.- Conduct the global F-Test for model utility using α = .05. Interpret the results, practically.

What material would typically have such a hardness value : What material would typically have such a hardness value? If a Brinell hardness test were to be conducted on this material, give an estimate of the indentation diameter if the load used was 1500 kg.

How many different gene marker combinations are possible : How many different gene marker combinations are possible at the two locations? List them.- Using dummy variables, write a model for extent of the disease, y, as a function of gene marker combination.

Model for wine quality as function of grape picking method : Create the appropriate dummy variables for each of the qualitative independent variables.- Write a model for wine quality (y) as a function of grape-picking method. Interpret the β's in the model.

Identify what can go wrong with financial reporting : Use the Argosy University online library resources and find at least three scholarly journal articles. These articles will help you identify what can go wrong with financial reporting and how this should be prevented.

What can you say about effect of coaching on sat math scores : The estimate of β2 in the model was 19, with a standard error of 3. Use this information to form a 95% confidence interval for β2. Interpret the interval.

Explain value based management and shareholder value : MS6010 - M1A3: Explain value based management and shareholder value. What are some of the rights of shareholders in companies today? What is a financial audit?

User Account

All Pages