Reference no: EM132458998
Question 1) Do inhibitory neurotransmitters activate or inhibit receptors? Inhibit receptors
Question 2) What is the major inhibitory neurotransmitter in the brain? gaba
Question 3) What is the major excitatory neurotransmitter in the brain? glutamate
Question 4) What is different between GABAA receptors and GABAB receptors? GABAa- ion channels GABAb- metabotrophic receptor
Question 5) How is GABA terminated? reuptake into both presynaptic nerve terminals and surrounding glial cells.
Question 6) What is the receptor for Glutamate? What kind of receptor is it? Ionotrophic an ion channel
Question 7) How is Glutamate terminated? the synaptic cleft by excitatory amino-acid transporters
Question 8) What role does dopamine play in the brain? Neurotransmitter that releases a "happy" chemical
Question 9) Dopamine works via what kind of receptors? D1,D2,D3,D4,D5
Question 10) How is the dopamine signal terminated? reuptake back into the presynaptic neuron
Question 11) What role does serotonin play in the brain? regulate anxiety, happiness, and mood
Question 12) Serotonin is synthesized from what? amino acid L-Tryptophan
Question 13) What kind of receptors are there for serotonin? 5-hydroxytryptamine
Question 14) How is the serotonin signal terminated? reuptake or enzymatic breakdown
Question 15) Will the inhibition of a serotonin reuptake inhibitor lead to sleepiness? A depressed mood? Yes; no
Question 16) What is the role of a presynaptic serotonin receptor? inhibiting release of 5HT into the synaptic cleft
Question 17) What is the difference between SSRIs and SNRIs? SNRIs work slightly differently than SSRIs, though both increase the amount of serotonin available in the bloodstream. While SSRIs only block the reuptake of serotonin, SNRIs can also be used for pain relief and are more effective for different types of depression
Question 18) What do tricycle antidepressants bind to? What is the result?
Question 19) What does monoamine oxidase do? breaks down norepinephrine, serotonin, and dopamine
Question 20) What happens when you inhibit MAO? norepinephrine, serotonin, and dopamine are not broken down, increasing the concentration of all three neurotransmitters in the brain
Question 21) What must you warn patients about? Possible side effects
Question 22) How does lithium work? help strengthen nerve cell connections in brain regions that are involved in regulating mood, thinking and behavior
Question 23) Describe the mechanism of action and indication and how they are related for the following drugs:
a. Cymbalta
b. Effexor
c. Nardil
d. bupropion (Wellbutrin)
e. imipramine (Trofranil)
f. sertraline (Zoloft)
g. Lexapro (escitalopram)
h. Paxil
i. Buspirone (BuSpar)
Question 24) What do CNS depressants do? act on the brain by increasing activity of GABA, a chemical that slows brain activity
Question 25) What are the 4 classes of CNS depressants? Barbiturates, Benzodiazepines, stimulants
Question 26) How does methylphenidate hydrochloride (Ritalin) work? How does this relate to the role of dopamine? increasing the availability of the neurotransmitters norepinephrine and dopamine in your CNS connections
Question 27) What receptor do barbiturates bind to? What do they do?
Question 28) What receptor do benzodiazepines bind to? What do they do?
Question 29) What is lorazepam and how does it work?
Question 30) What are barbiturates used to treat?
Question 31) What are benzodiazepines used to treat?
Question 32) How does Xanax work? How does this relate to the role of GABA in the brain?
Question 33) What is Nembutal and how does it work?
Question 34) What is zolpidem (Ambien) and how does it work?
Question 35) What are the classes of antidepressants? (table 16.1)
Question 36) How do the side effects of SNRIs relate to the roles of the neurotransmitters affected?
Question 37) How do the side effects of MAOIs relate to the roles of the neurotransmitters affected?
Question 38) What are the positive and negative symptoms of schizophrenia?
Question 39) What receptor does schizophrenia seem to be associated with? How does this relate to the role of this neurotransmitter in the brain?
Question 40) What are the conventional antipsychotic drugs and how do they work?
Question 41) What are the Atypical antipsychotic drugs and how do they work?
Question 42) Describe extrapyramidal side effects
Question 43) What is haloperidol and how does it work?
Attachment:- brain.rar