How does this related to hemoglobinopathies

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What does it mean to have gene cluster that code for globin proteins that compose Hemoglobin? How does this related to Hemoglobinopathies?

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How does this related to hemoglobinopathies : What does it mean to have gene cluster that code for globin proteins that compose Hemoglobin? How does this related to Hemoglobinopathies?

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