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As the amino terminal signal sequence required for co-translational transport into the ER begins
to emerge from the ribosome, translation halts while the ribosome is directed to the ER membrane.
A. How does the inhibition in translation occur?
B. How does the ribosome get to the ER membrane?
C. How does the peptide get to the Sec61 translocator and through the translocator pore?
Briefly describe how the oxygen effect plays an important role in reducing the ability of a radiation oncologist to treat tumors with the high energy electron beams from accelerators in Radiation Oncology facilities.
Define stable equilibrium in population genetics. Describe the kind of data that you would need to collect about a population to conclude that it is in a stable equilibrium.
Develop a hypothesis relating to the amount of dissolved oxygen measured in the water sample and the number of fish observed in the body of water.
Calculate the osmotic pressure, at 30°C, of 58.5 grams of NaCl in 1 liter of solution against pure water with a membrane that separates the pure water and salt solution and is impermeable to NaCl but permeable to water.
What is meant by the 'cloning of a gene'? (Explain what it means from the perspective of the host bacteria)
Monkeys infected with "Devil Pox" survive depending on their genotype at a single locus. AA individuals survive 50% of the time. AB individuals survive 75% of the time.
A corporation has invented a new low-calorie sugar substitute. They wish to determine if the substitute might be carcinogenic, so they use it in the Ames test with Salmonella his mutants.
Leber's optic neuropathy is a genetic disease caused by a mutated gene carried in mitochondrial DNA. What would be the phenotype of their first child if a man with this disease married a woman who did not have the disease? What would be the result..
What are a restriction enzyme recognition site? in nature, what is the purpose of restriction enzymes?
Suppose that a new low calorie sweetener is developed. The structure is novel and is tested with the Ames test for mutagenicity.
What type of tissue would you choose if you wanted to produce clones? That is, if you wanted to produce a plant from a single cell? explain.
Explain the purpose of an enzyme. Enzymes can function in two different locations with respect to the cell. What are the two types or two locations? Which type is amylase?
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