How does the immune system reacts to cancer cells

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Assignment:

Are there non-self molecules that are recognizable by the immune system on tumors? What self molecules can cause cancer and are they recognizable?

• How does the immune system reacts to cancer cells? What is immunoediting?

• What are NK cells and what are they activated? How do they complement the CTL? What is the missing self model?

• What are the immune mechanisms (cells & cytokines) that eliminate cancer?

• What can be expected in the tumor microenvironment?

• What are there immune mechanisms that are double edged?

• What are the immune responses (cells & cytokines) that help cancer escape elimination?

• Are anti-tumor antibodies always protective? Why?

• What are the different forms of cancer immunotherapies? What is their characteristics and principle of mechanisms?

• What is checkpoint therapy and antibodies are used to block which molecules? What is its downside?

Reference no: EM133569977

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