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Case: Determining the effectiveness of bone marrow transplants.
"DNA fingerprinting can help doctors to monitor bone marrow transplants. Leukemia is a cancer of the bone marrow and the diseased marrow must be removed. The bone marrow makes new blood cells, so the leukemia sufferer will die without a transplant of healthy marrow. Doctors can quickly tell whether the transplant has succeeded by DNA typing of the patient and the donor. If the transplant has worked, a fingerprint from the patient's blood shows the donor's bands. But if the cancerous bone marrow has not been properly destroyed, then the cancerous cells multiply rapidly and the patient's own bands predominate." ("Our Ultimate Identity Card in Sickness and in Health," in "Inside Science", New Scientist, Nov. 16, 1991.)
Using the information above, answer the following questions:
Question 1. What is the history and background information on bone marrow transplants? Question 2. How effective is it? Question 3. How does DNA typing aid in the success of the transplant?Question 4. What significant role has DNA typing played to monitor bone marrow transplants?
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