Reference no: EM132931571

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BIOLOGY CASE SCENARIO

Medical biology is the cornerstone of modern health care and laboratory diagnostics. It concerns a wide range of scientific and technological approaches: from an in vitro diagnostics[1][2] to the in vitro fertilization,[3] from the molecular mechanisms of a cystic fibrosis to the population dynamics of the HIV, from the understanding molecular interactions to the study of the carcinogenesis,[4] from a single-nucleotide polymorphism (SNP) to the gene therapy. Medical biology based on molecular biology combines all issues of developing molecular medicine[5] into large-scale structural and functional relationships of the human genome, transcriptome, proteome and metabolome with the particular point of view of devising new technologies for prediction, diagnosis and therapy.

1. In molecular biology, __________ methylation results to the aspect of genetic __________ within the progeny. What is the effect of this aspect?

2. Within a progeny, strictly _________ of the _________ genes congenital from _________ parent is _________. Give an identity to this trait.

1. The functional _________ is recognized as _________ in the phenomenon of allelic _________. What is the identity of the portrayed trait?

2. Identify an example of an imprinted gene in mammals. What is its role? Which replica of the gene is transcribed? IS IT EXPRESSED?

3. How do we refer to the X- chromosome incapacitation?

4. How is incapacitation of X-chromosome achieved? Explain.

5. Who suggested the idea of placental X-chromosome incapacitation? When?

6. Make a conclusion on the validity of the statement below.

During dosage reimbursement, the maternal X-chromosome is incapacitated.

7. Why are female mammals referred to as genetic mosaics?

8. In molecular biology, chemical analysis indicates that incapacitated X chromosome condenses into a dark staining arrangement. What is the identity of this arrangement and who was it named after?

9. Given A strand of RNA is composed of 20% adenine and 30% guanine.

What is the strand's composition of the other bases?

10. From molecular biology, what identity is given to an arrangement that has hydrogen bonds between polypeptide chains arranged side by side?