How do oral infections lead to arterial damage

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Reference no: EM133442071

Atherosclerosis in Adulthood

Results: This study included 755 participants, of whom 371 (49.1%) were male; the mean (SD) age at baseline examination was 8.07 (2.00) years. In this cohort, 33 children (4.5%) had no sign of oral infections, whereas 41 (5.6%) had 1 sign, 127 (17.4%) had 2 signs, 278 (38.3%) had 3 signs, and 248 (34.1%) had 4 signs. The cumulative exposure to risk factors increased with the increasing number of oral infections both in childhood and adulthood. In multiple linear regression models, childhood oral infections, including signs of either periodontal disease (R2 = 0.018; P = .01), caries (R2 = 0.022;)

Conclusions & Relevance: Oral infections in childhood appear to be associated with the subclinical carotid atherosclerosis seen in adulthood (Pussinen et al., 2019, p. 1)

1) How do oral infections lead to arterial damage?

2) What conclusions can you draw from this study?

3) What connections can you make between the research studies and the influence S. mutans has on the formation of dental carries in marginalized communities (e.g. low-SES, race)?

Reference no: EM133442071

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