How can we explain the existence of huntington

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Question: Huntington disease is an autosomal dominant inherited progressive brain disorder that causes uncontrolled movements, emotional problems, and loss of thinking ability (cognition). Adult-onset Huntington disease, the most common form of this disorder, usually appears in a person's 30's or 40's. Early signs and symptoms can include irritability, depression, small involuntary movements, poor coordination, and trouble learning new information or making decisions.

Affected individuals may have trouble walking, speaking, and swallowing. People with this disorder also experience changes in personality and a decline in thinking and reasoning abilities. Individuals with the adult-onset form of Huntington disease usually live about 15 to 20 years after signs and symptoms begin (NIH Genetics Home Reference).

We learned in class that selection eliminates harmful dominant alleles in a single generation. How can we explain the existence of Huntington (and many other) autosomal dominant diseases in an evolutionary context?

Reference no: EM133561822

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