HMG7210 Biostatistics Assignment

Assignment Help Basic Statistics
Reference no: EM132623656

HMG7210 Biostatistics - Victoria University

Assessment

Learning outcome 1: Elaborate fundamental concepts in biostatistics in public health emphasizing the disciplines of nutrition and active living;

Learning outcome 2: Appraise the commonly used methods of analysis of data and exhibit specialised skills in handling data sets;

Learning outcome 3: Apply appropriate statistical methods to the design of a public health research study;

Learning outcome 4: Perform basic statistical analyses and present findings in a clear, concise and logical manner accessible to specialist and non-specialist audiences; and

Learning outcome 5: Critically evaluate statistical methods described and applied in global nutrition and active living literature in order to substantiate their potential contribution to the broader public health evidence-base.

Part 1 - Dyslipidaemia Study

For Part 1 you will need the dataset Dyslipidaemia.sav

A cross-sectional study was conducted on 366 diabetic patients to assess their blood lipid profile and to investigate possible factors contributing to the development of dyslipidaemia among diabetic patients. The patients were recruited from a specialized hospital outpatient department. All study participants provided a blood sample and completed a lifestyle and demographic questionnaire.

The objective of the study was to find factor(s) that may relate to the risk of developing dyslipidaemia in diabetic patients. Along with the demographic information and physical measurements, haematological measurements were reported on a continuous scale. For analysis purposes most of the continuous variables were transformed into grouped data. However, original continuous variables were also kept in the data set. The short and long names of the variables and corresponding statistical codes are presented in the following table, Table 1.

Question 1: Complete the column "Variable type", listing each of the variables as either nominal, ordinal, discrete or continuous.

Table 1: Variable description of the Dyslipidaemia study

Variable

Variable label

Value label

Variable type

ID

ID Number

NA

 

Age

age of patients

NA

 

Age_gr

age categories

1              < 40 years

2              40 - 49 years

3              50 - 59 years

4              >= 60 years

 

Gender

patients gender

1              Male

2              Female

 

Occupation

Occupation type

1              Sedentary worker

2              Moderate worker

3              Heavy physical worker

 

Physical_activity

Physical activity level

0              Sufficient PA

1              Insufficient PA

 

weight

weight of patients

NA

 

Height

height of patients

NA

 

BMI

body mass index of patients

NA

 

BMI_gr

body mass index category

0              Normal

1              Overweight

2              Obese

 

BP_diastolic

diastolic blood pressure

NA

 

BP_systolic

systolic blood pressure

NA

 

HTN

Hypertension

0              Normotensive

1              Hypertensive

 

Duration_diabetes

Duration of Diabetes

NA

 

Duration_diabetes_gr

Duration category

1              < 5 years

2              5 - <10 years

3              > = 10 years

 

HbA1c

Fasting HbA1c level

NA

 

HbA1c_gr

HbA1c categories

0              <7 Controlled

1              >=7 Uncontrolled

 

Insulin

Takes insulin

0              No

1              Yes

 

Duration_insulin

Duration of insulin (years)

NA

 

T.Chol

Total Cholesterol

NA

 

T_Chol_gr

Cholesterol category

0              < 200

1              >= 200

 

TG

Triglyceride

NA

 

TG_gr

Triglyceride category

0              < 150

1              >= 150

 

HDL

HDL Cholesterol

NA

 

HDL_gr

HDL category

0              Normal

1              Low

 

LDL

LDL Cholesterol

NA

 

LDL_gr

LDL category

0              < 100

1              >= 100

 

Creatinine

Serum Creatinine

NA

 

Createnine_gr

Creatinine category

0              < 1.5

1              >=1.5

 

TC_HDL

TC_HDL ratio

NA

 

LDL_HDL

LDL_HDL ratio

NA

 

Dyslipidemia

Dyslipidaemia

0              No dislipidemia

1              Dislipidemia

 

Question 2 Part a)Fill out the following table using appropriate summary statistics for each of the listed variables. The outcome variable is dyslipidaemia.

Variable

Dyslipidaemia (% or median & IQR or mean & SD)

Yes

No

HbA1c

 

 

BP diastolic

 

 

Insulin status:

 

 

Yes

 

 

No

 

 

Age group:

 

 

< 40 yrs.

 

 

40 - 49 yrs.

 

 

50 - 59

 

 

≥ 60 yrs.

 

 

Question 2 Part b) Discuss whether dyslipidaemia is related to HbA1c, diastolic BP, insulin status and patients' age.
- Evaluate the conditions (if any) that you should check before reporting summary statistics for each of the numerical variables in this question.
- Present the relevant analysis output below, along with the table/graph number and appropriate title for the table/graph (copy and paste all analysis output in a picture format by using "Copy Special").
- Discuss the results and make a brief summaryconclusion in the context of the study. Please present the discussion and conclusion separately.

Question 3: Graphically determine the relationship between dyslipidaemia and each of the following variables: duration of diabetes group, BMI group and occupation type. Present each of the above variables on an appropriate graph and discuss. In this task you will need to: a) Justify the choice of the graphs that have been used; b) Discuss the results and make a brief summary conclusion in the context of the study, and c) Present the graphs in the text along with the graph number and appropriate title for the graph (copy and paste all graphs in a picture format, see the instructions provided in Question 2 above)

Part 2-Cardiovascular Disease Study

For Part 2 you will need the dataset CVD-Data.sav
Consider a study where twelve baseline variables (e.g., age, gender, weight, BMI, etc.) among others were collected from each of the 1429 participants. Out of the 1429 participants, 952 had a history of being treated with Drug-X on a regular basis. The objective of the study was to investigate whether Drug-X was protective for various risk factors of cardiovascular vascular disease (CVD). The participants were then followed for 5 years and their mortality status was recorded. The short and long names of the variables are given in Table 2.

Table 2. Variable description for cardiovascular disease study

Variable

Description

Statistical code (if any)

AGE

Age

N/A

GENDER

Gender

0 for female and 1 for male

WEIGHT

Weight

N/A

BMI

Body mass index

0 for <25; 1 for 25 to <30; 2 for 30 to <35 and 3 for 35 and above

SBP

Systolic blood pressure

N/A

DBP

Diastolic blood pressure

N/A

CHL

Cholesterol level

N/A

SMOKE

Smoking status

0 for never smoked and 1 for smoked

Drug-X

Drug "X" treated

0 for no and 1 for yes

PAD

Peripheral arterial disease

0 for no and 1 for yes

STROKE

Stroke

0 for no and 1 for yes

DEATH

Follow-up mortality status

0 for no and 1 for yes

Question 4: Consider that an investigator aims to assess whether followed-up mortality (DEATH) was related to body mass index (BMI, a categorical variable) in the study sample. Evaluate the investigator's aim by presenting the related data on an appropriate graph. (note: no additional summary statistics or significance test required).

Question 5: Using an appropriate graphical presentation, discuss whether diastolic blood pressure (DBP) is related to body mass index (BMI, a categorical variable) in the study sample (note: no additional summary statistics or significance test is required). Based on the findings can you make an inference on the study population? Justify your answer.

Instructions for Questions 6 & 7:

- Justify the choice of the statistical methods that have been used,
- Present the data analysis output graphs/tables along with the graph/table number and appropriate title for the graph/table (please use the special copy and paste option when copying and pasting from SPSS),
- For statistical significance tests, please follow the steps that have been outlined in the lecture and tutorial slides. All steps should be in the context of the study. Note: Interpretation for some of the results are required.
- Please do not discuss the steps of significance tests for each of the variables separately. Instead combine SBP, DBP and CHL in each step. Note: Five marks (5 marks) will be allocated for successful combination of the results.

Question 6: Using appropriate statistical method(s) investigate whether patients who had a history of being treated with Drug-X on a regular basis have significantly different systolic blood pressure (SBP), diastolic blood pressure (DBP) and cholesterol level (CHL) compared to patients who were not treated with Drug-X. In this task you will need to:
Please fill out the following table from the above analysis results

Variable

Summary Statistics

p-value

95% CI (where appropriate)

Yes Drug-X

No Drug-X

Systolic blood pressure

 

 

 

 

Diastolic blood pressure

 

 

 

 

Cholesterol level

 

 

 

 

Question 7 Using an appropriate statistical method evaluate the significance of difference of SBP across the following categories of BMI: BMI <25, BMI 25 to <30 and BMI ≥ 30kg/m2.

Reference no: EM132623656

Questions Cloud

Why do not just show the net balance of accounts receivable : Why don't just show the net balance of accounts receivable? Why bother showing the deduction of the allowance account on the balance sheet?
Calculate the discounted cash flow value for pdi : Calculate the discounted cash flow value for PDI. Future cash flows, A potential investment in Peltier Devices, Inc (PDI) is currently under review.
Topic of trust within your workplace : Write a paper addressing the topic of Trust within your workplace. What does trust look like from your standpoint?
Targeting card processing in eastern europe : There was a surge of attacks on banks where the attackers were targeting card processing in Eastern Europe.
HMG7210 Biostatistics Assignment : HMG7210 Biostatistics Assignment Help and Solution, Victoria University - Assessment Writing Service - appropriate statistical method evaluate the significance
What is meant by the underlying assumption going concern : ABC is an international supermarket chain selling food, Explain what is meant by the underlying assumption 'Going concern' when preparing financial statements.
Describe the four main parts of plato : Identify and describe the four main parts of Plato's. What are the three most important themes in Plato's account of the interior of the Cave?
Dividend per share of adelaide mining company : What is the dividend per share of Adelaide Mining Company? What is the value of a share of Adelaide Mining Company?
Developing an action plan : Outline the action plan (who, what, and when) that you would use in order to effectively implement your strategy.

Reviews

len2623656

9/7/2020 2:12:50 AM

please do it very carefully as it is very umportant and please put all the necessary tables and charts and graphs from the spss output.

Write a Review

Basic Statistics Questions & Answers

  Statistics-probability assignment

MATH1550H: Assignment:  Question:  A word is selected at random from the following poem of Persian poet and mathematician Omar Khayyam (1048-1131), translated by English poet Edward Fitzgerald (1808-1883). Find the expected value of the length of th..

  What is the least number

MATH1550H: Assignment:  Question:     what is the least number of applicants that should be interviewed so as to have at least 50% chance of finding one such secretary?

  Determine the value of k

MATH1550H: Assignment:  Question:     Experience shows that X, the number of customers entering a post office during any period of time t, is a random variable the probability mass function of which is of the form

  What is the probability

MATH1550H: Assignment:Questions: (Genetics) What is the probability that at most two of the offspring are aa?

  Binomial distributions

MATH1550H: Assignment:  Questions:  Let’s assume the department of Mathematics of Trent University has 11 faculty members. For i = 0; 1; 2; 3; find pi, the probability that i of them were born on Canada Day using the binomial distributions.

  Caselet on mcdonald’s vs. burger king - waiting time

Caselet on McDonald’s vs. Burger King - Waiting time

  Generate descriptive statistics

Generate descriptive statistics. Create a stem-and-leaf plot of the data and box plot of the data.

  Sampling variability and standard error

Problems on Sampling Variability and Standard Error and Confidence Intervals

  Estimate the population mean

Estimate the population mean

  Conduct a marketing experiment

Conduct a marketing experiment in which students are to taste one of two different brands of soft drink

  Find out the probability

Find out the probability

  Linear programming models

LINEAR PROGRAMMING MODELS

Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd