Hiv rna levels taking dolutegravir plus

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Reference no: EM133729481

Question

A 53-year-old patient who has maintained suppressed HIV RNA levels taking dolutegravir plus tenofovir DF-emtricitabine for several years is asking to switch to a one-tablet daily regimen and the clinician is considering a switch to the dual antiretroviral regimen of once-daily dolutegravir-lamivudine. Prior to starting their first antiretroviral regimen, the patient had a baseline HIV drug resistance genotype that showed no mutations. They have never had a virologic breakthrough. Which one of the following statements is TRUE regarding this switch? An archive (DNA) genotype should be performed prior to making the switch This switch should not be made if the person has chronic hepatitis B virus infection For the switch to be safe, a person must have an estimated creatinine clearance above 90 mL/min This switch should not be made if the person has chronic hepatitis C virus infection.

Reference no: EM133729481

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