History of RBC transfusions

Reference no: EM133720030

Question

John Smith, age 45 years, is a known sickle cell patient in your hospital. He has developed multiple alloantibodies because of his history of RBC transfusions. Anti-E, -K, -C, and -Doa antibodies have been previously identified. He now needs a transfusion of three RBC units. Compatible units are difficult to locate for him. No family member is antigen-negative for all these antibodies. Antisera for phenotyping RBC units for the Doa antigen is rare. What strategies can the blood bank pursue to provide Mr. Smith with antigen-negative compatible RBC units?

Reference no: EM133720030

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