History of heavy drinking

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52 y.o. male with long history of heavy drinking, reports daily consumption of 2 bottles wine. He denies other substance use and endorses symptoms of depression and insomnia. He meets criteria for alcohol use disorder (AUD), moderate severity, and endorses cravings for alcohol. Liver function enzymes are elevated 2 Xs upper limit of normal; macrocytosis is only other lab abnormality. He denies symptoms of alcohol withdrawal or history of complicated withdrawal. He has never received treatment for AUD or psychiatric disorder. He has a history of chronic lower back pain for which he takes lowdose oxycodone 1-2 X/s month during "flare-ups."

1. Is naltrexone contraindicated in this patient? Which medication would you consider for treatment of alcohol use disorder in this patient?

2. Under what circumstance would you consider disulfiram?

3. Under what circumstance would you consider combining medications?

4. What should you recommend in addition to medications?

Reference no: EM133804623

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